Anti-SYBL1/VAMP-7 antibody [158.2],Abcam,AB36195

Host

Mouse

Reactivity

Rat, Human

Application

IHC-Fr, ICC/IF, WB, Flow Cyt, IHC-P

Platform ID

BAB985061410

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-SYBL1/VAMP-7 antibody [158.2]
Cat. No.AB36195
HostMouse
IsotypeIgG1
ReactivityRat, Human
ApplicationIHC-Fr, ICC/IF, WB, Flow Cyt, IHC-P
ClonalityMonoclonal
Clone Number158.2
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human VAMP7.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: 2% Sucrose, 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation. See full target information VAMP7

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