Anti-Sarcomeric Alpha Actinin antibody [EA-53],Abcam,AB9465

Anti-Sarcomeric Alpha Actinin antibody [EA-53] (ab9465) is a House Mouse Monoclonal antibody and is validated for use in IHC-P, WB in human, mouse, rat samples. Anti-Sarcomeric Alpha Actinin antibody [EA-53] (ab9465) has been cited over 277 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality validation processes ensure Anti-Sarcomeric Alpha Actinin antibody [EA-53] (ab9465) has high sensitivity and specificity. Anti-Sarcomeric Alpha Actinin antibody [EA-53] (ab9465) has 12 independent reviews from customers. Anti-Sarcomeric Alpha Actinin antibody [EA-53] (ab9465) specifically detects Sarcomeric Alpha Actinin (UniProt ID: P35609; Molecular weight: 104kDa) and is sold in 100 uL selling sizes. Sarcomeric Alpha Actinin is a crucial protein in the muscle cytoskeleton, specifically localized at the Z-disc. The alpha actinin molecular weight is approximately 100 kDa, and it plays a vital role in maintaining sarcomere integrity. The a-actinin (ACTN2) antibody is essential tools for studying this protein's function. Abnormalities in alpha actinin are linked to various muscle diseases, including hypertrophic cardiomyopathy and nemaline myopathy, highlighting its disease relevance. This product was changed from ascites to tissue culture supernatant on 9 th September 2019. Lot numbers higher than GR3258034 are from tissue culture supernatant. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team. Storage in "frost-free" freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

Host

Mouse

Reactivity

Rat, Human, Mouse

Application

IHC-P, ICC/IF, WB

Platform ID

BAB151515267

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Sarcomeric Alpha Actinin antibody [EA-53]
Cat. No.AB9465
HostMouse
IsotypeIgG1
ReactivityRat, Human, Mouse
ApplicationIHC-P, ICC/IF, WB
ClonalityMonoclonal
Clone NumberEA-53
Concentration1 mg/mL Batch dependent concentration
PurityProprietary technique
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. See full target information ACTN2

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