Anti-Scavenging Receptor SR-BI antibody [EPR20190],Abcam,AB217318
What is this antibody validated in? Anti-Scavenging Receptor SR-BI antibody [EPR20190] (ab217318) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Scavenging Receptor SR-BI? Anti-Scavenging Receptor SR-BI [EPR20190] (ab217318) specifically detects a band for Scavenging Receptor SR-BI (UniProt: Q8WTV0) at a molecular weight of 60kDa. Trusted by the scientific community Anti-Scavenging Receptor SR-BI [EPR20190] (ab217318) was first used in a scientific publication in 2017 and has been cited over 40 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Scavenging Receptor SR-BI antibody [EPR20190] (ab217318) has been confirmed by Western blot testing in SCARB1 Knockout HAP1 cells. Other related products We have a range of other formats of antibody clone [EPR20190] also available for your convenience: ab217318, Carrier free - ab222931 , Carrier free - ab272003 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
IP, ICC/IF, IHC-P, WB
Platform ID
BAB528201957
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed : 12016218, PubMed : 12519372, PubMed : 21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed : 26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed : 12016218).. (Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes and appears to facilitate its cell entry (PubMed : 12356718, PubMed : 12913001, PubMed : 18000990). Binding between SCARB1 and the hepatitis C virus glycoprotein E2 is independent of the genotype of the viral isolate (PubMed : 12356718).. (Microbial infection) Mediates uptake of M.fortuitum, E.coli and S.aureus.. (Microbial infection) Facilitates the entry of human coronavirus SARS-CoV-2 by acting as an entry cofactor through HDL binding. See full target information SCARB1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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- Products>Primary Antibodies>Recombinant Antibodies
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