Anti-Slit1 antibody,Abcam,AB10984

Host

Rabbit

Reactivity

Mouse, Rat

Application

WB

Platform ID

BAB723941750

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Slit1 antibody
Cat. No.AB10984
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationWB
ClonalityPolyclonal
Concentration1.2 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Mouse Slit1 aa 450-550 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.01% Sodium azide Constituents: 0.88% Sodium chloride, 0.424% Potassium phosphate solution
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. See full target information Slit1

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