Anti-Smac/Diablo antibody,Abcam,AB8115

Host

Rabbit

Reactivity

Rat, Mouse

Application

WB

Platform ID

BAB724341558

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Smac/Diablo antibody
Cat. No.AB8115
HostRabbit
IsotypeIgG
ReactivityRat, Mouse
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Mouse Diablo aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification DEAE-C
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/BRUCE by inhibiting its binding to caspases (By similarity). See full target information Diablo

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