Anti-SmarcAL1 antibody,Abcam,AB236786

Host

Rabbit

Reactivity

Mouse, Human

Application

WB, ICC/IF

Platform ID

BAB100128680

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-SmarcAL1 antibody
Cat. No.AB236786
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB, ICC/IF
ClonalityPolyclonal
Concentration3 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human SMARCAL1 aa 1-300. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks. See full target information SMARCAL1

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