Anti-Soluble TNF Receptor I antibody,Abcam,AB9979
Host
Rabbit
Reactivity
Human
Application
sELISA, WB, ELISA
Platform ID
BAB414933823
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-Soluble TNF Receptor I antibody
Cat. No.AB9979
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationsELISA, WB, ELISA
ClonalityPolyclonal
ImmunogenRecombinant Full Length Protein corresponding to Human TNFRSF1A.
PurityAffinity purification Immunogen
Appearance/FormLyophilized
ShippingBlue Ice
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. See full target information TNFRSF1A
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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