Anti-Soluble TNF Receptor II antibody,Abcam,AB109853
Host
Rabbit
Reactivity
Human
Application
I-ELISA, sELISA, WB, FuncS (Neut/Block)
Platform ID
BAB602477552
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-Soluble TNF Receptor II antibody
Cat. No.AB109853
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationI-ELISA, sELISA, WB, FuncS (Neut/Block)
ClonalityPolyclonal
ImmunogenRecombinant Full Length Protein corresponding to Human TNFRSF1B.
PurityAffinity purification Immunogen
Appearance/FormLyophilized
ShippingBlue Ice
FormulationConstituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. See full target information TNFRSF1B
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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