Anti-Solute carrier family 22 member 5 antibody,Abcam,AB180757

Target data Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine (PubMed : 10454528, PubMed : 10525100, PubMed : 10966938, PubMed : 17509700, PubMed : 20722056, PubMed : 33124720). Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 11.3 (PubMed : 10454528, PubMed : 10525100, PubMed : 10966938). In intestinal epithelia, transports the quorum-sensing pentapeptide CSF (competence and sporulation factor) from Bacillus Subtilis wich induces cytoprotective heat shock proteins contributing to intestinal homeostasis (PubMed : 18005709). May also contribute to regulate the transport of organic compounds in testis across the blood-testis-barrier (Probable).. Isoform 3. Retained in the ER, unable to perform carnitine uptake. See full target information SLC22A5