Anti-Stra8 antibody,Abcam,AB49405

Target data Meiosis-inducer required for the transition into meiosis for both female and male germ cells (PubMed : 16461896, PubMed : 17115059, PubMed : 18799751, PubMed : 18799790, PubMed : 19805549, PubMed : 32032549, PubMed : 32054698). In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program : required for premeiotic DNA replication and subsequent events in meiotic prophase (PubMed : 16461896, PubMed : 17115059, PubMed : 18799751, PubMed : 18799790, PubMed : 32054698). During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation (PubMed : 25902548). In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis (PubMed : 19805549, PubMed : 32032549). See full target information Stra8