Anti-Synaptophysin antibody [YE269] - Synaptic Marker,Abcam,AB32127

Anti-Synaptophysin antibody [YE269] (ab32127) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-P and WB. Anti-Synaptophysin antibody [YE269] (ab32127) was first used in a scientific publication in 1986 and has been cited over 311 times in peer reviewed journals. It's performance in Western blot and IHC in mouse samplesis trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Synaptophysin antibody [YE269] (ab32127) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Synaptophysin antibody [YE269] (ab32127) has been confirmed by Western Blot testing in Synaptophysin knockout HEK-293T cells ( ab255356 ). Anti-Synaptophysin antibody [YE269] (ab32127) has 38 independent reviews from customers. Anti-Synaptophysin antibody [YE269] (ab32127) specifically detects Synaptophysin (UniProt ID: P08247; Molecular weight: 34kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone YE269 - ab187259 . Antibody clone YE269 is also available pre-conjugated to a variety of labels for your convenience - HRP, Alexa Fluor ® 647, Alexa Fluor ® 488, Alexa Fluor ® 594, Alexa Fluor ® 555, ( ab195520 , ab196166 , ab196379 , ab206868 , ab206870 , ). Synaptophysin (SYP) is a key protein in neuro research, particularly for its role as a marker of synaptic vesicles. It is involved in synaptic transmission and vesicle trafficking. Researchers use synaptophysin to study synaptic density and integrity, making it essential for understanding synaptic function and dysfunction in various neurological conditions, including Alzheimer's disease (AD) and schizophrenia. Its expression helps in assessing synaptic health and the effects of neurodegenerative diseases on synaptic connectivity. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

WB, ICC/IF, IHC-P

Platform ID

BAB860498700

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Synaptophysin antibody [YE269] - Synaptic Marker
Cat. No.AB32127
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, ICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberYE269
Concentration0.28 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). See full target information SYP

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