Anti-Synaptotagmin antibody [ASV30],Abcam,AB13259
This product was changed from ascites to tissue culture supernatant on 5th July 2019. Lot numbers higher than GR3258922 are from tissue culture supernatant. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
Host
Mouse
Reactivity
Mouse, Rat
Application
WB, ICC/IF, IP
Platform ID
BAB610573664
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties (PubMed : 7961887). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (PubMed : 7961887). Plays a role in dendrite formation by melanocytes (By similarity).. (Microbial infection) Receptor for C.botulinum neurotoxin type B (BoNT/B, botB); interaction is improved in the presence of gangliosides (PubMed : 14504267). The toxin binds via the vesicular domain (residues 47-60) (PubMed : 14504267, PubMed : 17167418, PubMed : 23807078).. (Microbial infection) Receptor for C.botulinum neurotoxin type G (BoNT/G, botG); gangliosides are not required for (or only very slightly improve) binding to a membrane-anchored receptor fragment (PubMed : 20219474). The toxin binds via the vesicular domain (residues 47-55) (PubMed : 20219474). See full target information Synaptotagmin-2
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
Please provide the required information below so that we can quickly source your products.