Anti-Synphilin 1 antibody,Abcam,AB6179
This antibody stains Lewy bodies in Dorsal raphe nucleus of Parkinson's diseased human brain.
Host
Rabbit
Reactivity
Rat
Application
IHC-P
Platform ID
BAB673354779
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-Synphilin 1 antibody
Cat. No.AB6179
HostRabbit
IsotypeIgG
ReactivityRat
ApplicationIHC-P
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human Synphilin-1 aa 900 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 7.4
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1. See full target information Synphilin-1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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