Anti-TACC3 antibody,Abcam,AB245455

Host

Rabbit

Reactivity

Human

Application

WB, IP

Platform ID

BAB111623160

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-TACC3 antibody
Cat. No.AB245455
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, IP
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human TACC3 aa 400-500. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: Tris buffered saline, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as a component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed : 21297582, PubMed : 23532825). May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed : 14767476). See full target information TACC3

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.