Anti-TAF7 antibody [2C5],Abcam,AB57494

This product was changed from ascites to tissue culture supernatant on 12 th June 2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.

Host

Mouse

Reactivity

Human

Application

Flow Cyt, WB, IHC-P

Platform ID

BAB361848052

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TAF7 antibody [2C5]
Cat. No.AB57494
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationFlow Cyt, WB, IHC-P
ClonalityMonoclonal
Clone Number2C5
ImmunogenRecombinant Fragment Protein within Human TAF7 aa 100-250. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed : 33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed : 33795473). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed : 10438527, PubMed : 33795473). TAF7 forms a promoter DNA binding subcomplex of TFIID, together with TAF1 and TAF2 (PubMed : 33795473). Part of a TFIID complex containing TAF10 (TFIID alpha) and a TFIID complex lacking TAF10 (TFIID beta) (PubMed : 10438527). See full target information TAF7

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.