Anti-TBLR1/TBL1XR1 antibody [4F3-A8-D9],Abcam,AB117761

This product was changed from ascites to tissue culture supernatant on 17.08.2018. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.

Host

Mouse

Reactivity

Human, African green monkey, Mouse

Application

ICC/IF, IHC-P, WB

Platform ID

BAB925978519

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-TBLR1/TBL1XR1 antibody [4F3-A8-D9]
Cat. No.AB117761
HostMouse
IsotypeIgG1
ReactivityHuman, African green monkey, Mouse
ApplicationICC/IF, IHC-P, WB
ClonalityMonoclonal
Clone Number4F3-A8-D9
ImmunogenRecombinant Fragment Protein within Human TBL1XR1. The exact immunogen used to generate this antibody is proprietary information.
PurityCross-flow filtration
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation. See full target information TBL1XR1

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