Anti-TBR2 / Eomes antibody,Abcam,AB23345

Tbr2 expression is observed in neuron progenitor compartments in development (the subventricular zone and ventricular zone) and expression rises and falls with cortical plate neurogenesis. Transition from radial glia to intermediate progenitor cell is associated with upregulation of Tbr2. Product Specifications Anti-TBR2 / Eomes antibody (ab23345) is a rabbit polyclonal antibody and is validated for use in IHC-Fr, WB in human, mouse samples. Anti-TBR2 / Eomes antibody (ab23345) specifically detects TBR2 / Eomes (UniProt ID: O95936; Molecular weight: 73kDa) and is sold in 50 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-TBR2 / Eomes antibody (ab23345) has high sensitivity and specificity. Anti-TBR2 / Eomes antibody (ab23345) has been cited over 530 times in peer reviewed journals and is trusted by the scientific community. Anti-TBR2 / Eomes antibody (ab23345) has 37 independent reviews from customers.

Host

Rabbit

Reactivity

Mouse, Human

Application

IHC-Fr, WB

Platform ID

BAB926078471

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TBR2 / Eomes antibody
Cat. No.AB23345
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationIHC-Fr, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. See full target information Eomes

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