Anti-TEAD4 antibody [5H3],Abcam,AB58310
What is this antibody validated in? Anti-TEAD4 antibody [5H3] (ab58310) is a mouse monoclonal antibody and is validated for use in Western Blot (WB) in Human samples. What is the molecular weight of TEAD4? Anti-TEAD4 [5H3] (ab58310) specifically detects a band for TEAD4 (UniProt: Q15561) at a molecular weight of 48kDa. Trusted by the scientific community Anti-TEAD4 [5H3] (ab58310) was first used in a scientific publication in 2007 and has been cited over 90 times in peer-reviewed journals.
Host
Mouse
Reactivity
Human
Application
WB
Platform ID
BAB927377847
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif. See full target information TEAD4
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
Please provide the required information below so that we can quickly source your products.