Anti-THEM4 antibody,Abcam,AB106435

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, ICC/IF, IHC-P

Platform ID

BAB429326911

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-THEM4 antibody
Cat. No.AB106435
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationWB, ICC/IF, IHC-P
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human THEM4. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed : 11598301, inhibits AKT1 phosphorylation and activity. According to PubMed : 17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane. See full target information THEM4

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.