Anti-TIMP1 antibody [EPR18352],Abcam,AB211926

What is this antibody validated in? Anti-TIMP1 antibody [EPR18352] (ab211926) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. What is the molecular weight of TIMP1? Anti-TIMP1 [EPR18352] (ab211926) specifically detects a band for TIMP1 (UniProt: P01033) at a molecular weight of 23kDa. Trusted by the scientific community Anti-TIMP1 [EPR18352] (ab211926) was first used in a scientific publication in 2016 and has been cited over 30 times in peer-reviewed journals. Reviewed by scientists Anti-TIMP1 [EPR18352] (ab211926) has over 10 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-TIMP1 antibody [EPR18352] (ab211926) has been confirmed by Western blot testing in TIMP1 Knockout HeLa cells. Other related products We have a range of other formats of antibody clone [EPR18352] also available for your convenience: ab211926, Carrier free - ab219471 , Biotin - ab317768 , Alexa Fluor® 488 - ab321852 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

ICC/IF, WB, IHC-P

Platform ID

BAB369144548

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TIMP1 antibody [EPR18352]
Cat. No.AB211926
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, WB, IHC-P
ClonalityMonoclonal
Clone NumberEPR18352
Concentration2.386 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. See full target information TIMP1

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