Anti-TLR3 antibody [40C1285],Abcam,AB13915
Host
Mouse
Reactivity
Mouse, Human
Application
Flow Cyt (Intra), IHC-P, WB
Platform ID
BAB245181550
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-TLR3 antibody [40C1285]
Cat. No.AB13915
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationFlow Cyt (Intra), IHC-P, WB
ClonalityMonoclonal
Clone Number40C1285
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human TLR3 aa 50-100 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. See full target information TLR3
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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