Anti-TLR3 antibody,Abcam,AB62566
What is this antibody validated in? Anti-TLR3 antibody (ab62566) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human, Mouse, Rat samples. What is the molecular weight of TLR3? Anti-TLR3 (ab62566) specifically detects a band for TLR3 (UniProt: O15455) at a molecular weight of 104kDa. Trusted by the scientific community Anti-TLR3 (ab62566) was first used in a scientific publication in 2008 and has been cited over 50 times in peer-reviewed journals. Reviewed by scientists Anti-TLR3 (ab62566) has over 10 independent reviews from customers.
Host
Rabbit
Reactivity
Rat, Mouse, Human
Application
WB, ICC, IHC-P
Platform ID
BAB870194044
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-TLR3 antibody
Cat. No.AB62566
HostRabbit
IsotypeIgG
ReactivityRat, Mouse, Human
ApplicationWB, ICC, IHC-P
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human TLR3 aa 750-850. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. See full target information TLR3
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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