Anti-TLR3 antibody [HL2314],Abcam,AB317197

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cat, Dog

Application

WB, IHC-P

Platform ID

BAB995256514

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TLR3 antibody [HL2314]
Cat. No.AB317197
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Cat, Dog
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberHL2314
ImmunogenRecombinant Fragment Protein within Human TLR3.
Regulatory StatusResearch Use Only

Scientific Background

Target data Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. See full target information TLR3

Category Paths

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