Anti-TLR3 antibody [TLR3.7],Abcam,AB12085
Host
Mouse
Reactivity
Human
Application
Flow Cyt (Intra)
Platform ID
BAB307762761
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-TLR3 antibody [TLR3.7]
Cat. No.AB12085
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt (Intra)
ClonalityMonoclonal
Clone NumberTLR3.7
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human TLR3.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. See full target information TLR3
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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