Anti-TMEM119 antibody [106-6] - Microglial marker,Abcam,AB210405

What is this antibody validated in? Anti-TMEM119 antibody [106-6] - Microglial marker (ab210405) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt) in Mouse samples. What is the molecular weight of TMEM119? Anti-TMEM119 [106-6] - Microglial marker (ab210405) specifically detects a band for TMEM119 (UniProt: Q8R138) at a molecular weight of 29kDa. Trusted by the scientific community Anti-TMEM119 [106-6] - Microglial marker (ab210405) was first used in a scientific publication in 2016 and has been cited over 10 times in peer-reviewed journals. Reviewed by scientists Anti-TMEM119 [106-6] - Microglial marker (ab210405) has over 5 independent reviews from customers. Specificity confirmed The specificity of Anti-TMEM119 antibody [106-6] - Microglial marker (ab210405) has been confirmed by Flow Cytometry testing in Tmem119 Knockout Mouse microglia samples. Other related products We have a range of other formats of antibody clone [106-6] also available for your convenience: ab210405, Carrier free - ab220249 , Alexa Fluor® 647 - ab225494 , PE - ab225496 , Alexa Fluor® 488 - ab225497 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human, Mouse

Application

WB, ICC/IF, Flow Cyt

Platform ID

BAB808412449

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TMEM119 antibody [106-6] - Microglial marker
Cat. No.AB210405
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ApplicationWB, ICC/IF, Flow Cyt
ClonalityMonoclonal
Clone Number106-6
Concentration0.205 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays an important role in bone formation and normal bone mineralization (PubMed : 20025746, PubMed : 22416756, PubMed : 26207632). Promotes the differentiation of myoblasts into osteoblasts (PubMed : 20025746, PubMed : 22416756, PubMed : 22579779). May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway (PubMed : 21239498, PubMed : 22579779). Up-regulates the expression of ATF4 which plays a central role in osteoblast differentiation (PubMed : 24362451). Essential for normal spermatogenesis and late testicular differentiation (PubMed : 26207632). See full target information Tmem119

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