Anti-TMEM119 antibody [28-3] - Microglial marker,Abcam,AB209064
Anti-TMEM119 antibody [28-3] - Microglial marker (ab209064) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in IHC-FoFr, IHC-Fr and IHC-P Anti-TMEM119 antibody [28-3] - Microglial marker (ab209064) was first used in a scientific publication in 2016 and has been cited over 139 times in peer reviewed journals. It's performance in IHC and Immunofluorescence in mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-TMEM119 antibody [28-3] - Microglial marker (ab209064) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-TMEM119 antibody [28-3] - Microglial marker (ab209064) has been confirmed by IHC testing in TMEM119 knockout Mouse brain cells. Anti-TMEM119 antibody [28-3] - Microglial marker (ab209064) has 20 independent reviews from customers. Anti-TMEM119 antibody [28-3] - Microglial marker (ab209064) specifically detects TMEM119 (UniProt ID: Q4V9L6; Molecular weight: 27kDa) and is sold in a convenient trial size to enable initial testing (10 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone 28-3 - ab234501 . TMEM119 is a marker for microglia, the resident immune cells of the brain. In Alzheimer's disease (AD) research, TMEM119 is used to differentiate microglia from other brain-resident cells and infiltrating macrophages. Altered TMEM119 expression in AD brains reflects microglial activation and neuroinflammation, making it a valuable tool for studying the immune response and pathology in Alzheimer's disease. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents .
Host
Rabbit
Reactivity
Mouse
Application
IHC-Fr, IHC-P, IHC-FoFr
Platform ID
BAB433424943

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Plays an important role in bone formation and normal bone mineralization (PubMed : 20025746, PubMed : 22416756, PubMed : 26207632). Promotes the differentiation of myoblasts into osteoblasts (PubMed : 20025746, PubMed : 22416756, PubMed : 22579779). May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway (PubMed : 21239498, PubMed : 22579779). Up-regulates the expression of ATF4 which plays a central role in osteoblast differentiation (PubMed : 24362451). Essential for normal spermatogenesis and late testicular differentiation (PubMed : 26207632). See full target information Tmem119
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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