Anti-TNF Receptor I antibody [55R-170],Abcam,AB106099
Host
Armenian hamster
Reactivity
Mouse
Application
Flow Cyt
Platform ID
BAB497205578
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-TNF Receptor I antibody [55R-170]
Cat. No.AB106099
HostArmenian hamster
IsotypeIgG1
ReactivityMouse
ApplicationFlow Cyt
ClonalityMonoclonal
Clone Number55R-170
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human TNFRSF1A. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. See full target information TNFRSF1A
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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