Anti-TNF Receptor I antibody,Abcam,AB223352
What is this antibody validated in? Anti-TNF Receptor I antibody (ab223352) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse samples. What is the molecular weight of TNF Receptor I? Anti-TNF Receptor I (ab223352) specifically detects a band for TNF Receptor I (UniProt: P19438) at a molecular weight of 50.5kDa.
Host
Rabbit
Reactivity
Mouse, Human
Application
ICC/IF, WB, IHC-P
Platform ID
BAB434724319
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. See full target information TNFRSF1A
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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