Anti-TNF Receptor II antibody [MR2-1],Abcam,AB8161
Host
Mouse
Reactivity
Human
Application
Flow Cyt, ICC/IF
Platform ID
BAB559786789
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-TNF Receptor II antibody [MR2-1]
Cat. No.AB8161
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt, ICC/IF
ClonalityMonoclonal
Clone NumberMR2-1
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human TNFRSF1B. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. See full target information TNFRSF1B
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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