Anti-TOM70 antibody,Abcam,AB89624

Target data Acts as a receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) (PubMed : 12526792). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (PubMed : 12526792, PubMed : 35025629). Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection (PubMed : 20628368, PubMed : 25609812, PubMed : 32728199). Upon Sendai virus infection, recruits HSP90AA1 : IRF3 : BAX in mitochondrion and the complex induces apoptosis (PubMed : 25609812). See full target information TOMM70