Anti-TOMM20 antibody [EPR15581-39] - Mitochondrial Marker,Abcam,AB186734
What is this antibody validated in? Anti-TOMM20 antibody [EPR15581-39] - Mitochondrial Marker (ab186734) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of TOMM20? Anti-TOMM20 [EPR15581-39] - Mitochondrial Marker (ab186734) specifically detects a band for TOMM20 (UniProt: Q15388) at a molecular weight of 16kDa. Trusted by the scientific community Anti-TOMM20 [EPR15581-39] - Mitochondrial Marker (ab186734) was first used in a scientific publication in 2014 and has been cited over 90 times in peer-reviewed journals. Reviewed by scientists Anti-TOMM20 [EPR15581-39] - Mitochondrial Marker (ab186734) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR15581-39] also available for your convenience: ab186734, Alexa Fluor® 488 - ab205486 , Alexa Fluor® 647 - ab205487 , HRP - ab205796 , Alexa Fluor® 555 - ab214409 , Carrier free - ab220822 , ab283317 , Carrier free - ab283339 , ab289670 , Carrier free - ab289676 , Alexa Fluor® 488 - ab309083 , Alexa Fluor® 647 - ab309166 , Alexa Fluor® 647 - ab309167 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
WB, Flow Cyt (Intra), ICC/IF, IHC-P
Platform ID
BAB372842772
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Central receptor component of the translocase of the outer membrane of mitochondria (TOM) complex essential for the recognition and translocation of cytosolically synthesized mitochondrial preproteins (PubMed : 40080546). Together with TOMM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (PubMed : 18331822). The TOM complex associates with the ion channel VDAC2 and PINK1 kinase at depolarized mitochondria, this interaction stabilizes PINK1 at the outer mitochondrial membrane and triggers downstream mitophagy by the recruitment of the E3 ubiquitin ligase PRKN (PubMed : 40080546). Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases (By similarity). See full target information TOMM20
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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