Anti-TOMM20 antibody [EPR15581-39] - Mitochondrial Marker - Rat IgG2a (Chimeric),Abcam,AB289670

What is this antibody validated in? Anti-TOMM20 antibody [EPR15581-39] - Rat IgG2a (Chimeric) (ab289670) is a rat recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of TOMM20? Anti-TOMM20 [EPR15581-39] - Rat IgG2a (Chimeric) (ab289670) specifically detects a band for TOMM20 (UniProt: Q15388) at a molecular weight of 16kDa. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR15581-39] also available for your convenience: ab186734 , Alexa Fluor® 488 - ab205486 , Alexa Fluor® 647 - ab205487 , HRP - ab205796 , Alexa Fluor® 555 - ab214409 , Carrier free - ab220822 , ab283317 , Carrier free - ab283339 , ab289670, Carrier free - ab289676 , Alexa Fluor® 488 - ab309083 , Alexa Fluor® 647 - ab309166 , Alexa Fluor® 647 - ab309167 What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rat

Reactivity

Mouse, Human, Rat

Application

WB, ICC/IF, Flow Cyt (Intra), IHC-Fr, IHC-P

Platform ID

BAB997855266

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TOMM20 antibody [EPR15581-39] - Mitochondrial Marker - Rat IgG2a (Chimeric)
Cat. No.AB289670
HostRat
IsotypeIgG2a
ReactivityMouse, Human, Rat
ApplicationWB, ICC/IF, Flow Cyt (Intra), IHC-Fr, IHC-P
ClonalityMonoclonal
Clone NumberEPR15581-39
Concentration0.965 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityIon exchange chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Central receptor component of the translocase of the outer membrane of mitochondria (TOM) complex essential for the recognition and translocation of cytosolically synthesized mitochondrial preproteins (PubMed : 40080546). Together with TOMM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (PubMed : 18331822). The TOM complex associates with the ion channel VDAC2 and PINK1 kinase at depolarized mitochondria, this interaction stabilizes PINK1 at the outer mitochondrial membrane and triggers downstream mitophagy by the recruitment of the E3 ubiquitin ligase PRKN (PubMed : 40080546). Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases (By similarity). See full target information TOMM20

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