Anti-TOMM20 antibody [EPR15581-54] - BSA and Azide free,Abcam,AB232589

What is this antibody validated in? Anti-TOMM20 antibody [EPR15581-54] - BSA and Azide free (ab232589) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of TOMM20? Anti-TOMM20 [EPR15581-54] - BSA and Azide free (ab232589) specifically detects a band for TOMM20 (UniProt: Q15388) at a molecular weight of 16kDa. Other related products We have a range of other formats of antibody clone [EPR15581-54] also available for your convenience: ab186735 , Alexa Fluor® 647 - ab209606 , HRP - ab209951 , Alexa Fluor® 405 - ab210047 , Alexa Fluor® 594 - ab210665 , Alexa Fluor® 568 - ab210841 , Alexa Fluor® 555 - ab221292 , APC - ab225341 , PE - ab225342 , Carrier free - ab232589, Alexa Fluor® 488 - ab320072 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-Fr, ICC/IF, WB, IHC-P, Flow Cyt (Intra)

Platform ID

BAB935374007

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TOMM20 antibody [EPR15581-54] - BSA and Azide free
Cat. No.AB232589
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-Fr, ICC/IF, WB, IHC-P, Flow Cyt (Intra)
ClonalityMonoclonal
Clone NumberEPR15581-54
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Central receptor component of the translocase of the outer membrane of mitochondria (TOM) complex essential for the recognition and translocation of cytosolically synthesized mitochondrial preproteins (PubMed : 40080546). Together with TOMM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (PubMed : 18331822). The TOM complex associates with the ion channel VDAC2 and PINK1 kinase at depolarized mitochondria, this interaction stabilizes PINK1 at the outer mitochondrial membrane and triggers downstream mitophagy by the recruitment of the E3 ubiquitin ligase PRKN (PubMed : 40080546). Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases (By similarity). See full target information TOMM20

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.