Anti-TPM4 antibody - N-terminal,Abcam,AB230880

Host

Rabbit

Reactivity

Human

Application

WB, IHC-P, Flow Cyt (Intra)

Platform ID

BAB748629894

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TPM4 antibody - N-terminal
Cat. No.AB230880
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, IHC-P, Flow Cyt (Intra)
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human TPM4 aa 1-100 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments (By similarity). Binds calcium (PubMed : 1836432). Plays a role in platelet biogenesis. See full target information TPM4

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