Anti-TRAIL antibody [2E5],Abcam,AB2219

Host

Mouse

Reactivity

Human

Application

FuncS

Platform ID

BAB311860793

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-TRAIL antibody [2E5]
Cat. No.AB2219
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFuncS
ClonalityMonoclonal
Clone Number2E5
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human TNFSF10 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed : 10549288, PubMed : 26457518). Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. See full target information TNFSF10

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