Anti-TRAP1 antibody,Abcam,AB151239

Host

Rabbit

Reactivity

Mouse, Human

Application

ICC/IF, WB

Platform ID

BAB375241620

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TRAP1 antibody
Cat. No.AB151239
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationICC/IF, WB
ClonalityPolyclonal
Concentration0.22 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human TRAP1 aa 350 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 10% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA. See full target information TRAP1

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