Anti-TRAP1 antibody [TRAP1-6],Abcam,AB2721

Host

Mouse

Reactivity

Mouse, Human

Application

IP, ICC/IF, IHC-P, WB

Platform ID

BAB937772855

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TRAP1 antibody [TRAP1-6]
Cat. No.AB2721
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationIP, ICC/IF, IHC-P, WB
ClonalityMonoclonal
Clone NumberTRAP1-6
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human TRAP1.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA. See full target information TRAP1

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