Anti-TRIOBP antibody - C-terminal,Abcam,AB151320

Host

Rabbit

Reactivity

Rat, Human

Application

IHC-P, WB, ICC/IF

Platform ID

BAB439122207

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-TRIOBP antibody - C-terminal
Cat. No.AB151320
HostRabbit
IsotypeIgG
ReactivityRat, Human
ApplicationIHC-P, WB, ICC/IF
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human TRIOBP aa 1800-2100. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Isoform 1. Regulates actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F-actin and prevents its depolymerization (PubMed : 18194665, PubMed : 28438837). May also serve as a linker protein to recruit proteins required for F-actin formation and turnover (PubMed : 18194665). Essential for correct mitotic progression (PubMed : 22820163, PubMed : 24692559).. Isoform 5. Plays a pivotal role in the formation of stereocilia rootlets.. Isoform 4. Plays a pivotal role in the formation of stereocilia rootlets. See full target information TRIOBP

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