Anti-TRPC6 antibody [3F2.H10.F2],Abcam,AB105845

Host

Mouse

Reactivity

Mouse, Human

Application

IHC-P, WB, ELISA

Platform ID

BAB815109233

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TRPC6 antibody [3F2.H10.F2]
Cat. No.AB105845
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationIHC-P, WB, ELISA
ClonalityMonoclonal
Clone Number3F2.H10.F2
Concentration0.964 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.01% Sodium azide Constituents: 0.88% Sodium chloride, 0.424% Potassium phosphate solution
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Forms a receptor-activated non-selective calcium permeant cation channel (PubMed : 19936226, PubMed : 23291369, PubMed : 26892346, PubMed : 9930701). Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed : 26892346). Seems not to be activated by intracellular calcium store depletion. See full target information TRPC6

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