Anti-TSG101 antibody [4A10] - BSA and Azide free,Abcam,AB83
What is this antibody validated in? Anti-TSG101 antibody [4A10] - BSA and Azide free (ab83) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P) in Human, Mouse samples. What is the molecular weight of TSG101? Anti-TSG101 [4A10] - BSA and Azide free (ab83) specifically detects a band for TSG101 (UniProt: Q99816) at a molecular weight of 43kDa. Trusted by the scientific community Anti-TSG101 [4A10] - BSA and Azide free (ab83) was first used in a scientific publication in 1999 and has been cited over 290 times in peer-reviewed journals.
Host
Mouse
Reactivity
Mouse, Human
Application
IHC-P, Flow Cyt, WB
Platform ID
BAB003252674
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413). It may also play a role in the extracellular release of microvesicles that differ from the exosomes (PubMed : 22315426). See full target information Tumor susceptibility gene 101 protein
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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