Anti-TTF1/Nkx2-1 antibody [EPR5955(2)],Abcam,AB133737

What is this antibody validated in? Anti-TTF1/Nkx2-1 antibody [EPR5955(2)] (ab133737) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human, Mouse, Rat samples. What is the molecular weight of TTF1/Nkx2-1? Anti-TTF1/Nkx2-1 [EPR5955(2)] (ab133737) specifically detects a band for TTF1/Nkx2-1 (UniProt: P43699) at a molecular weight of 39kDa. Trusted by the scientific community Anti-TTF1/Nkx2-1 [EPR5955(2)] (ab133737) was first used in a scientific publication in 2012 and has been cited over 20 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR5955(2)] also available for your convenience: ab133737, Alexa Fluor® 488 - ab206726 , Alexa Fluor® 647 - ab206727 , Carrier free - ab227574 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

WB, IHC-P

Platform ID

BAB566483573

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TTF1/Nkx2-1 antibody [EPR5955(2)]
Cat. No.AB133737
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberEPR5955(2)
Concentration1.647 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity). See full target information NKX2-1

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