Anti-TUFM antibody,Abcam,AB67991

Host

Mouse

Reactivity

Rat

Application

WB

Platform ID

BAB379439604

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-TUFM antibody
Cat. No.AB67991
HostMouse
IsotypeIgG
ReactivityRat
ApplicationWB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human TUFM.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Also plays a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIGI-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy. See full target information TUFM

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