Anti-Tau Alzheimer’s Disease antibody [GT-38] - Conformation-Specific,Abcam,AB246808

What is this antibody validated in? Anti-Tau Alzheimer’s Disease antibody [GT-38] - Conformation-Specific (ab246808) is a mouse monoclonal antibody and is validated for use in Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), ELISA in Human samples. Other related products We have a range of other formats of antibody clone [GT-38] also available for your convenience: ab246808, Carrier free - ab254274 , Alexa Fluor® 488 - ab317594 , Alexa Fluor® 594 - ab317763 , Alexa Fluor® 647 - ab317764 , Alexa Fluor® 555 - ab320065 Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Human

Application

IHC-Fr, ELISA, IHC-P

Platform ID

BAB800116433

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tau Alzheimer’s Disease antibody [GT-38] - Conformation-Specific
Cat. No.AB246808
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC-Fr, ELISA, IHC-P
ClonalityMonoclonal
Clone NumberGT-38
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS, 6.97% L-Arginine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by the MAPT gene promotes microtubule assembly and stability and might be involved in establishing and maintaining neuronal polarity. Its C-terminus binds axonal microtubules, and the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between the two. Axonal polarity is predetermined by MAPT localization within the neuronal cell's domain defined by the centrosome. The short isoforms allow cytoskeleton plasticity, whereas the longer isoforms may preferentially play a role in its stabilization. This supplementary information is collated from multiple sources and compiled automatically. See full target information MAPT

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.