Anti-Tau antibody,Abcam,AB75714

Two different affinity purified anti peptide antibodies were combined to make this product. The concentrations of both of these antibodies was 100 μg/ml, making the total antibody concentration 200 μg/ml.

Host

Chicken

Reactivity

Human, Mouse, Rat

Application

IHC-P, ICC/IF, WB, ICC

Platform ID

BAB050141421

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tau antibody
Cat. No.AB75714
HostChicken
IsotypeIgY
ReactivityHuman, Mouse, Rat
ApplicationIHC-P, ICC/IF, WB, ICC
ClonalityPolyclonal
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human MAPT conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by the MAPT gene promotes microtubule assembly and stability and might be involved in establishing and maintaining neuronal polarity. Its C-terminus binds axonal microtubules, and the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between the two. Axonal polarity is predetermined by MAPT localization within the neuronal cell's domain defined by the centrosome. The short isoforms allow cytoskeleton plasticity, whereas the longer isoforms may preferentially play a role in its stabilization. This supplementary information is collated from multiple sources and compiled automatically. See full target information MAPT

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