Anti-Tau (phospho S396) antibody [E178],Abcam,AB32057

Product Specifications Anti-Tau (phospho S396) antibody [E178] (ab32057) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in AP, Dot blot, ELISA, IHC-Fr, IHC-P, IP, WB in human, mouse, rat samples. Anti-Tau (phospho S396) antibody [E178] (ab32057) specifically detects Tau Phospho-S396 (UniProt ID: P10636; Molecular weight: 79kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-Tau (phospho S396) antibody [E178] (ab32057) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Tau (phospho S396) antibody [E178] (ab32057) has been cited over 72 times in peer reviewed journals and is trusted by the scientific community. Anti-Tau (phospho S396) antibody [E178] (ab32057) has 6 independent reviews from customers. Related Products Antibody clone E178 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 555, Alexa Fluor® 594, Alexa Fluor® 568, Alexa Fluor® 750 ( ab305369 , ab311642 , ab312915 , ab321561 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IP, WB, IHC-Fr, Dot, ELISA, IHC-P, AP

Platform ID

BAB738034982

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tau (phospho S396) antibody [E178]
Cat. No.AB32057
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIP, WB, IHC-Fr, Dot, ELISA, IHC-P, AP
ClonalityMonoclonal
Clone NumberE178
Concentration0.101 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by the MAPT gene promotes microtubule assembly and stability and might be involved in establishing and maintaining neuronal polarity. Its C-terminus binds axonal microtubules, and the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between the two. Axonal polarity is predetermined by MAPT localization within the neuronal cell's domain defined by the centrosome. The short isoforms allow cytoskeleton plasticity, whereas the longer isoforms may preferentially play a role in its stabilization. This supplementary information is collated from multiple sources and compiled automatically. See full target information MAPT phospho S396 Additional targets MAPT phospho S396

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.