Anti-Tau (phospho S396) antibody [EPR2731],Abcam,AB109390

Tau is a protein associated with several disease states, known collectively as tauopathies. The most well-known of these is Alzheimer's disease (AD), were tau exhibiting excessive phosphorylation, aggregating to form neurofibrillary tangles. The epitope defined by phosphorylation of S396 in tau is strongly implicated in AD-associated tau pathology, providing a valuable target for the development of therapeutic antibodies to capture tau and prevent spreading of tau pathology. Product Specifications Anti-Tau (phospho S396) antibody [EPR2731] (ab109390) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Dot blot, IHC-Fr, IHC-P, IP, WB in human, mouse, rat samples. Anti-Tau (phospho S396) antibody [EPR2731] (ab109390) specifically detects Tau Phospho-S396 (UniProt ID: P10636; Molecular weight: 79kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-Tau (phospho S396) antibody [EPR2731] (ab109390) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Tau (phospho S396) antibody [EPR2731] (ab109390) has been cited over 127 times in peer reviewed journals and is trusted by the scientific community. Anti-Tau (phospho S396) antibody [EPR2731] (ab109390) has 12 independent reviews from customers. Related Products Antibody clone EPR2731 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, Alexa Fluor® 555, Alexa Fluor® 488, Alexa Fluor® 594, Alexa Fluor® 568 ( ab300748 , ab302570 , ab302581 , ab302686 , ab302804 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .