Anti-Tau (phospho S404) antibody [EPR2605],Abcam,AB92676

What is this antibody validated in? Anti-Tau (phospho S404) antibody [EPR2605] (ab92676) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), Immunocytochemistry/immunofluorescence (ICC/IF), Dot Blot in Human, Mouse, Rat samples. What is the molecular weight of Tau? Anti-Tau (phospho S404) [EPR2605] (ab92676) specifically detects a band for Tau (UniProt: P10636) at a molecular weight of 79kDa. Trusted by the scientific community Anti-Tau (phospho S404) [EPR2605] (ab92676) was first used in a scientific publication in 2010 and has been cited over 30 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR2605] also available for your convenience: ab92676, Carrier free - ab196364 , Alexa Fluor® 647 - ab311070 , Alexa Fluor® 594 - ab311656 , Alexa Fluor® 568 - ab312929 , Alexa Fluor® 555 - ab313142 , Alexa Fluor® 750 - ab321768 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

Dot, ICC/IF, IHC-Fr, IHC-P, IP, WB

Platform ID

BAB300566217

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tau (phospho S404) antibody [EPR2605]
Cat. No.AB92676
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationDot, ICC/IF, IHC-Fr, IHC-P, IP, WB
ClonalityMonoclonal
Clone NumberEPR2605
Concentration0.102 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.01% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by the MAPT gene promotes microtubule assembly and stability and might be involved in establishing and maintaining neuronal polarity. Its C-terminus binds axonal microtubules, and the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between the two. Axonal polarity is predetermined by MAPT localization within the neuronal cell's domain defined by the centrosome. The short isoforms allow cytoskeleton plasticity, whereas the longer isoforms may preferentially play a role in its stabilization. This supplementary information is collated from multiple sources and compiled automatically. See full target information MAPT phospho S404

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