Anti-Tenascin C antibody [DB7],Abcam,AB86182

ab86182 is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Host

Mouse

Reactivity

Human

Application

IHC-P, IP, ICC/IF, WB

Platform ID

BAB052640221

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tenascin C antibody [DB7]
Cat. No.AB86182
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationIHC-P, IP, ICC/IF, WB
ClonalityMonoclonal
Clone NumberDB7
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human TNC.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.1% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed : 19884327). See full target information TNC

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