Anti-Tetanus Toxin antibody [TH-11],Abcam,AB278064

Host

Mouse

Application

WB

Platform ID

BAB115521288

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Tetanus Toxin antibody [TH-11]
Cat. No.AB278064
HostMouse
IsotypeIgG1
ApplicationWB
ClonalityMonoclonal
Clone NumberTH-11
Concentration1 mg/mL Batch dependent concentration
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 5 - 8 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2. See full target information tetX Additional targets Tetanus Toxin

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