Anti-Tetanus Toxoid antibody [3F6],Abcam,AB191896

Host

Mouse

Reactivity

Clostridium tetani

Application

ELISA, cELISA

Platform ID

BAB678052523

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Tetanus Toxoid antibody [3F6]
Cat. No.AB191896
HostMouse
IsotypeIgG1
ReactivityClostridium tetani
ApplicationELISA, cELISA
ClonalityMonoclonal
Clone Number3F6
Concentration1.01 mg/mL Batch dependent concentration
ImmunogenFull Length Protein corresponding to Clostridium tetani E88 tetX aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2. See full target information tetX Additional targets Tetanus Toxoid

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